DEPARTMENT OF BIOCHEMISTRY





 

OTHER ACADEMIC ACTIVITIES

Training courses /conferences/workshops organized

  • MLT students from Board of Technical Education, New Delhi are trained on different laboratory procedures
  • Students of MD (pathology) are trained on chemical pathology
  • Ms. Nisha Kachchap has completed her dissertation for her MSc (Life Science), IGNOU
  • In service training for lab assistants from Govt of NCT Delhi
  • Mrs. Srijana Srestha, Asst. Prof (Biochemistry), BPKIHS, Nepal was trained on Molecular biology and immunology techniques.

Publications

  • Imtiyaz Ahmad, Rashid Mir,Mariyam Zuberi, Jamsheed Javid, Prasant Yadav, Shazia Farooq, M. Masroor, Sameer Guru, Sheikh Shahnawaz, PC Ray, Ishfaq Ahmed Sheikh, Tanvir Khatlani, Ajaz Ah Bhat, Naresh Gupta, Sunita Jetly, Niyaz Ahmad and Alpana Saxena, Inactivation of RIZ1 Gene by Promoter Hypermethylation is Associated with Disease Progression and Resistance to Imatinib in Indian Chronic Myelogenous Leukemia Patients, First Study from India, J Cancer Sci Ther,2013,Vol.5.2 :045-051.
  • Rashid Mir, Mariyam Zuberi, Imtiyaz Ahmad, Jamsheed Javid, Prasant Yadav, Shazia Farooq, M Masroor, Sameer Guru, Sheikh Shanawaz, Ajaz Ah Bhat ,Tanvir S Khatlani, Sunita Jetly, P C Ray, Naresh Gupta, and Alpana Saxena, Biological and Clinical Implications of Exon 8 P53 (R282W) Gene Mutation in Relation to Development and Progression of Chronic Myeloid Leukaemia Patients in Indian Population, J Cell Sci Ther 2013, 4:140.
  • Jamsheed J, Mir Rashid, Masroor M, Imtiyaz A, Shazia F, Prasant Y, Mariyam Z, AA Bhat, Ishfaq Ah Sheikh, Khalani T, Julka PK, Maqbol L, P C Ray and Alpana Saxena, TP53 is a Mutational Target in Non Small Cell Lung Cancer Patients and its Pro/Pro Variant is Potentially Contributing to Cancer Susceptibility, J Carcinogene Mutagene 2013, 4:138.
  • Imtiyaz Ah,Mir Rashid,Sameer G.,Jamsheed J.,Mariyam Z,Shazia F.,Prasant Y.,Masroor M.,Ajaz Bhat,Sheikh Ishfaq,Naveen Kumar,Khaiani T.,Naresh Gupta. P C Ray and Alpana Saxena, Inactivation of P16 (INK 4a)gene by promoter hypermethylation is associated with disease progression in Chronic Myelogenous Leukemia,J Carcinogene and Mutagene,2013,4 : 141.
  • Dholariya S, Zuberi M, Ray PC, Gandhi G, Khurana N, Yadav P, Mahapatra S, Javid J, Ahmad I, Saxena A, Mir Rashid. TP53 gene polymorphism in epithelial ovarian carcinoma patients from north Indian population and its Pro/Pro varient is potentially contributing to cancer susceptibility. J Genetic Syndrome and Gene Therapy 3013:4;5
  • Karlo J, Bhat BV, Koner BC, Adhisivam B. (2013) Evaluation of Renal Function in Term Babies with Perinatal Asphyxia.Indian J Pediatr. [Epub ahead of print]
  • Mohapatra S, Saxena A, Gandhi G, Koner BC, Ray PC.( 2013) Vitamin D and VDR gene polymorphism (FokI) in epithelial ovarian cancer in Indian population.J Ovarian Res. 6(1):37.
  • Sagar Dholariya, Maryam Zuveri, Imtiaz Ahmad, Jamsheed Javid, Prasant Yadav, P.C.Ray-Tp53 gene polymorphismin epithelial overian carcinoma patients from North Indian population and its pro/pro variant is potentially contributing to cancer susceptibility. J. Genetic Syndrome & Gene Therapy 2013,
  • Mathur N.B., Garg A., Mishra T.K.: Role of dexamethasone in neonatal meningitis;a randomized controlled trial. Indian J Pediatr.80(2):102-7Feb.2013
  • Sunita Mahajan A.S., Jain A.K., Singh N.P., Mishra T.K.: Heart rate and blood pressure response to exercise and recovery in sub clinical hypothyroid patients. Int.J Appl.& Basic Med. Res:3(2):106-110,2013
  • Pandey S.K., Singh A., Dubey A.P. Mishra T.K., Kapoor S. Heparin Co-factor II Thrombin Complex as a Biomarker for Micropolysacchiodosis: Indian Experience. Indian Pediatr.(accepted for publication.)
  • Baidarbhi Chakraborty, Gaurav Vishnoi, Binita Goswami, Srinivas H. Gowda, Debashish Chowdhury, Sarita Agarwal. (2013) Lipoprotein(a), Ferritin, and Albumin in Acute Phase Reaction Predicts Severity and Mortality of Acute Ischemic Stroke in North Indian Patients. Journal of Stroke and Cerebrovascular Diseases Volume 22, Issue7
  • Adila Parveen, Rashmi Babbar, Sarita Agarwal, Anita Kotwani, Mohammad Fahim. Terminalia arjuna Enhances Baroreflex Sensitivity and Myocardial Function in Isoproterenol-Induced Chronic Heart Failure Rats. J Cardiovasc Pharmacol Ther 2012; 17: 199-207

Books written/edited/chapters contributed:

  • Practical Manual of Biochemistry for M.B.B.S.(2nd Edition) has been written by Dr. S.K. Gupta, Dr. V.S.Gehlaut and Dr. Anju Jain.
  • Practical Manual of Biochemistry for B.D.S. (2nd Edition) has been written by Dr. S.K. Gupta, Dr. V.S.Gehlaut and Dr. Anju Jain.

Conferences /workshops attended:

  • Dr. A. Saxena attended DBT sponsored Cancer Informatics Workshop titled-Next Generation Data Analysis, at ACTREC, Tata Memorial Center, Mumbai, from Jan 28-30, 2013.
  • Dr. A. Saxena attended American Association for Clinical Chemistry (AACC) Annual Meeting 2013,held on July 28- August 1, 2013,at Houston, Texas , USA
  • Dr. Sarita Agarwal, Dr. T. K. Mishra, Dr. S.K. Gupta. Dr. P. C. Ray, Dr. Pramod Lali and Dr Smita Kaushik attended 20th National Conference of Association of Medical Biochemists of India (AMBI) held at CMC,Ludhiana, Punjab from 15-17th Dec, 2013 and chaired different scientific sessions of the conference.
  • National Conference on “Zoonotic Mycobacterial infections and their impact on public Health” held on February 25th to 27th, 2013 at AIIMS, New Delhi was attended by Dr. P. C. Ray.
  • Dr. Sarita Agarwal, Dr. S. K. Gupta, Dr T. K. Mishra, Dr. P. C. Ray, Dr. P. Lali and Dr. Smita Kaushik attended CMC (Advances in Clinical Biochemistry and Medical Education) held at Biochemistry Department, UCMS & GTB Hospital on 30th Sept,2013
  • International Conference on “Recent Advances in Molecular Mechanisms of Neurological Disorders” held on 21st to 23rdFebruary, 2013 at AIIMS, New Delhi was attended by Dr. P. C. Ray
  • Dr. A. Saxena, Dr. S. Agarwal, Dr. S. K. Gupta, Dr. T. K. Mishra, Dr. P. C. Ray and Dr. Smita Kaushik attended and chaired sessions in the National conference of Association of Clinical Biochemists of India (ACBICON- 2013) held on 3rd – 6th December 2013, at Delhi.
  • Dr. Lal Chandra presented a poster in 5th International Congress on Prediabetes and Metabolic syndrome in Vienna, Austria on April 18-20, 2013
  • Dr. Lal Chandra and Dr. Dnyanesh Amle attended International conference on molecular pathology and 2nd annual conference of MPA. at Raipur on 9-10 Feb. 2013.
  • Dr. Smita Kaushik attended International conference on Inborn Errors of Metabolism and Indian conference of ISIEM at SGR Hospital(5-7 April,2013)
  • Dr. Kajal attended “Workshop on Laboratory diagnosis of Inborn error of metabolism.” held at RML hospital New Delhi on 4th April 2013.
  • Dr. Kajal, Dr. Dnyanesh Amle, Dr. Sagar Dholariya, Dr. Elvia, Dr. Kritika, Dr. Aditi, Dr. Ashikh, Dr. Rashmi, Dr. Raja, Dr. Namrata, Dr. Kamlesh and Dr S. Singh attended CME on advances in "Clinical Biochemistry and Medical Education" held at UCMS , New Delhi on 30th Sep. 2013.
  • Dr. Kajal attended 4th International Conference on Stem Cells and Cancer (ICSCC-2013), Mumbai on 19-22th October 2013.
  • Dr. Kajal and Dr. Dnyanesh attended Pre-conference workshop on Nanotechnology in Medicine and Pharmacology.at CMC, Ludhiana on 14thNov, 2013.
  • Dr. Dnyanesh and Dr. Sagar Dholariya was awarded 1st Prize in AMBICON National PG Quiz 2013

Poster presentation at conferences:

  • Rashid Mir, Imtiyaz Ahmad, Mariyam Zuberi, Jamsheed Javid, Shazia Farooq, Sameer Guru, Prasant Yadav, P.C. Ray, Naresh Gupta, Masroor Mirza, Alpana Saxena. Detection of JAK2 V617F and JAK2 exon 12 mutations in chronic myeloid leukemia patients and their role in disease progression. at American Association for Clinical Chemistry (AACC) Annual Meeting 2013,held on July 28- August 1, 2013,at Houston, Texas, USA
  • Mariyam Zuberi , AB Mir , Imtiyaz Ahmad , J. Javid, P. Yadav, M. Masroor, S. Guru, S. Dholariya, P.C Ray, G. Gandhi, Alpana Saxena. Diagnostic and prognostic association of epigenetic inactivation of DAPK1 and p16 genes in Epithelial Ovarian Carcinoma patients.at American Association for Clinical Chemistry (AACC) Annual Meeting 2013,held on July 28- August 1, 2013 at Houston, Texas , USA
  • Das S, Gupta SK, Girish MP, Ray PC. Lipoprotein associated phospholipase A2 (LpPLA2) as better marker than highly sensitive C reactive protein (hsCRP and Lipoprotein a) in Indians with coronary artery disease. Dr. S Das got student research award at AACC annual meeting 2013 at Houston, Texus, USA
  • Reetika Saini, P. Lali, S.Ramji, Vedika Bhat, BC Koner. Effect of severe perinatal asphexia on pituitary and thyroid function in the new born. 8th Asia Pacific Regional Meeting of the International Society for neonatal screening. 27-29 Sept, 2013 at AIIMS, New Delhi. Dr Reetika got best poster award for the presentation.
  • Megha Bhongade, S. Prasad, RC Jiloha, PC Ray, BC Koner. Source of stressors and mechanism of stress-induced infertility among male subjects. Conjoint meeting of the international federation of fertlity societies and the American Society for Reproductive Medicine. 12-17th October, 2013 at Boston, MA, USA.
  • Megha Bhongade, S. Prasad, RC Jiloha, PC Ray, BC Koner. Seminal plasma protein carbonyl ans serum testosterone level in stress-induced alteration of seminal quality in mal partner of infertile couple. 20th Association of Medical Biochemists of India held on 14-17, November, 2013 at CMC, Ludhiana, India.
  • Shazia R Fraooq, Ab Rashid Mir, Mariyam Zuberi, Jamsheed Javid, Prashant Yadav, Sameer Guru, M A Siddiqui, Alpana Saxena, P C Ray. Evaluation of Radioprotective property of Podophyllum hexandrum by increasing antioxidant activities in Mouse Model, presented at AMBICON-2013 held at Ludhaina Punjab on 15-17th November 2013
  • Dyanesh Amle, Alka Khaneja, Sarita Agarwal, P.C. Ray, Ravinder Ahlawat, Rashid Mir, Prasant Yadav, Alpana Saxena. Association of VEGF gene 18 bp I/D polymorphism with Diabetic Nephropathy. Presented at AMBICON-2013 held at Ludhiana, Punjab, held on 15-17th November, 2013
  • Sagar Dholariya, Mariyam Zuberi, AB Rashid Mir, Prasant Yadav, Sudeshna Mohapatra, Gauri Gandhi, Nita Khurana, Alpana Saxena and Prakash C Ray. Association of MDM 309 T>G promoter single nucleotide polymorphism with Epithelial Ovarian Cancer (EOC) in north Indian population. presented at AMBICON-2013 held at Ludhiana, Punjab, held on 15-17th November, 2013
  • Dr. Kajal, Dr. Rashid Mir, Prasant Yadav, Dr. P.C. Ray, Dr. Nita Khurana, Dr. P.N. Agarwal and Dr. Alpana Saxena. BRCA1 promoter hypermethylation in serum DNA of sporadic breast cancer. at AMBI Delhi chapter CME 2013
  • Dr. Kajal, Dr. Rashid mir, Prasant Yadav, Dr. P.C. Ray, Dr. Nita Khurana, Dr. P.N. Agarwal and Dr. Alpana Saxena. Aberrant promoter methylation of BRCA1 in sporadic breast cancer. 4th International Conference on Stem Cells and Cancer (ICSCC-2013), Mumbai
  • Dr. Kajal, Dr. Rashid mir, Prasant Yadav, Dr. P.C. Ray, Dr. Nita khurana, Dr. P.N. Agarwal and Dr. Alpana Saxena. Promoter hypermethylation of tumor suppressor genes (RASSF1A and CDH1) in serum DNA of breast cancer patients. in the 21st National conference of Association Medical Biochemist of India (AMBICON-2013) held on 15-17th November, 2013 at CMC Ludhiana Punjab.
  • Dr. Kajal, Dr. Rashid mir, Prasant Yadav, Dr. P.C. Ray, Dr. Nita khurana, Dr. P.N. Agarwal and Dr. Alpana Saxena. RASSF1A and CDH1 promoter hypermethylation in circulating cell- free DNA of breast cancer patients as a diagnostic biomarker. Selected for among best paper in SITA DEVI AWARD CATEGORY in National conference of Association Clinical Biochemist of india (ACBICON-2013) held on 3rd – 6th December 2013 at VMMC, Delhi.
  • Dr. Kajal, Dr. Rashid mir, Prasant Yadav, Dr. P.C. Ray, Dr. Nita khurana, Dr. P.N. Agarwal and Dr. Alpana Saxena. Serum based DNA hypermethylation: A new sensitive and promising biomarker in diagnosing breast cancer. 5th International Conference on Translational Cancer Research, 2013
  • Dnyanesh Amle, Alka Khaneja , Sarita Aggarwal, Ravinder Ahlawat, Rashid Mir, P C Ray, Alpna Saxena, Serum VEGF and VEGF gene polymorphism in patients with Diabetic Nephropathy : A therapeutic perspective. AMBICME, New Delhi, 2013
  • Dnyanesh Amle, Alka Khaneja , Sarita Aggarwal, Ravinder Ahlawat, Rashid Mir, P C Ray, Alpna Saxena, Study of VEGF gene polymorphism in patients with Diabetic Nephropathy at 2nd International conference on molecular pathology 2013, Raipur
  • Dr. Dholariya Sagar Jayantilal, Dr. Rashid Mir, Mariyam Zuberi, Prasant Yadav, Dr. Sudheshna Mohpatra, Dr. Alpana Saxena , Dr. Nita Khurana, Dr. Gauri Gandhi and Dr. P.C. Ray Association of MDM2 309 T>G promoter single nucleotide polymorphism with epithelial ovarian cancer in north Indian population 21st National Conference of AMBICON 2013. 15-17th November Ludhiana
  • Dr. S Dholariya. MDM2 309 T>G promoter single nucleotide polymorphism associated with increased risk and early age onset of Epithelial Ovarian Cancer(EOC) in north Indian population at 5th International Conference on Translational Cancer Research. 6-9th February New Delhi.
  • Onam Aggarwal, Pramod Lali, Lal chandra, Dinesh Dhanwal, Bidhan chandra koner.is insulin resistance a determinant of serum cystatin c levels as a marker of early nephropathy in metabolic syndome? at World congress on Insulin Resistance at Los Angeles, 2013. Received Young Intenational Reseach Scientist Award.
  • Dr Sapna Singh, Dr Girish M.P, Dr T.K. Mishra, Dr S.K. Gupta. Soluble cd40 ligand (scd40l) is a better indicator of marker of severity of coronary artery stenosis than hs-CRP.in the 21st National conference of Association Medical Biochemist of India (AMBICON-2013) held on 15-17th November 2013, at CMC Ludhiana Punjab

Representation on expert committees / bodies

  • Dr. A. Saxena was external examiner for Ph.D Biochemistry at AIIMS.
  • Dr. A. Saxena was external examiner for MD Biochemistry at AIIMS, New Delhi
  • Dr. S. Agarwal delivered Dr S.D. Mallikarjuna GL -Kodliwadhmath Oration in AMBICON 2013 – Ludhiana Titled "Lipids-A rugged journey of 100 years"
  • Dr. S. Agarwal was External examiner for M.D. Examinations to Kolkatta Medical College and Christian Medical College, Ludhiana
  • Dr. S. Agarwal was External examiner for MBBS exams to Government Medical College, Patiala
  • Dr. S. Agarwal moderated question papers of National board of examination
  • Dr. S. Agarwal reviewed a project report sponsored by Indian council of Medical Research
  • Dr. S. K. Gupta was external examiner for MD (Biochemistry) examination at PGI, Chandigarh in Nov, 2013
  • Dr. S. K. Gupta was member of Library committee.
  • Dr. S. K. Gupta as member of LAN committee
  • Dr. S. K. Gupta continues to be the President, Student’s Sports Committee of MAM college.
  • Dr. S. K. Gupta was external examiner for MBBS examination at Baba Farid University, Punjab
  • Dr. T. K. Mishra was an expert at the interview board of assit prof at VMMC,New Delhi
  • Dr. T. K. Mishra was paper setter for MD exam KIMS, Bhubaneshwar
  • Dr. T. K. Mishra was external examiner for MBBS,at G.S.T. Medical College, Gurgaon
  • Dr. T. K. Mishra continues to be the Store Officer of college
  • Dr. T. K. Mishra moderator of question paper of National Board Of Examinations
  • Dr. A. Khaneja was external examiner for BDS examination at PGIMS Rohtak
  • Dr. P. C. Ray is the secretary of Association of Medical Biochemist of India- Delhi State (AMBI-DELHI).
  • Dr. P. C. Ray was the External Examiner for MD(Biochemistry) at J N Medical College, AMU, Aligarh held in June,2013.
  • Dr. P. C. Ray was the Internal Examiner for MD(Biochemistry) for Delhi University, held in April 2013.
  • Dr. P. C. Ray evaluated two MD (Biochemistry) theses from Manipur University in the month of Feb. 2013.
  • Dr. P. Lali is the treasurer of Delhi state branch of Association of Medical Biochemists of India (AMBI)
  • Dr. P. Lali is nominated as member of the Purchase committee
  • Dr. P. Lali reviewed PhD thesis from Rajasthan University of Medical Sciences.
  • Dr. P. Lali was external examiner for MD (Biochemistry) examination at Swai Man Singh medical college at Jaipur.
  • Dr. P. Lali was external examiner for PhD (Biochemistry) examination at Swai Man Singh medical college at Jaipur.
  • Dr. P. Lali was member of interview board for selection of Residents and specialist.
  • Dr. P. Lali was member of interview board for selection of Assistant Professor on contract basis.
  • Dr. B. C. Koner reviewed manuscripts from CCA and Cellular immunology
  • Dr. B. C. Koner was external examiner for MBBS examination at Sarda University, NOIDA in July, 2013 and October, 2013
  • Dr. B. C. Koner was paper setter in National Board of Examination for MD Entrance Examination
  • Dr. Lal Chandra was external examiner for MD (Biochemistry) examination in Subharti Medical College, Meerut.
  • Dr. Lal Chandra was external examiner for MBBS examination in SRMS institute of Medical Sciences, Bareilly.
  • Dr. Smita Kaushik was external examiner at DMC Ludhiana, 10-12 July, 2013
  • Dr. Smita Kaushik was external examiner at MMInstitute of Medical Sciences and Research, Mullana, Ambala, Hayrana(31st Oct, 2013)
  • Dr. Smita Kaushik was external examiner at Subharti Medical college,Meerut(12-14 Aug 2013)
  • Dr. Smita Kaushik was external examiner at Sudha Rastogi College of Dental Sciences and Research, Faridabad(7-8 Aug 2013)
  • Dr. Smita Kaushik was Co-author in Elsevier Project for MBBS Consult
  • Dr. Smita Kaushik was invited as an expert by IGNOU for formulation of curriculum for 4yr degree course for MLT in the field of Biochemistry.
  • Dr. Smita Kaushik was superintendent of 1st MBBS(suppl) theory examination 2013(2-11 spt,2013)
  • Dr. Smita Kaushik was paper setter for MD (Biochemistry), 2013 and MPT, 2013 in Maharishi Markandeshwas University.

Health services to the community

  • All the senior residents, post graduates and technical staff participated in the ongoing Pulse Polio immunization programme of Govt of NCT of Delhi.
  • All the Residents do the night duties on rotational basis at Biochemistry Laboratory of LN Hospital to ensure the quality and smooth running of the lab.

LAB Data

A. Central Lab Services L. N. Hospital:

All routine biochemical tests.


  Special tests
Glycated Hemoglobin (HbA1c)
Serum CK total
Serum CKMB
Serum amylase
S. LDH
S. Ionized calcium
Urine sodium
Urine creatinine
Urine total proteins
Body fluid Biochemistry
ABG
GTT

Number of tests performed during 2013

MonthTotal no. of investigations
January2,08,265
February2,48,766
March2,44,440
April2,57,580
May2,23,461
June2,49,251
July2,57,978
August2,55,677
September2,53,645
October2,83,276
November2,76,971
December2,73,597
Total30,32,907

Number of investigation in 2013 :30,32,907
Percentage incease from last year: 15%
B. Electrophoresis Lab, MAMC:

Serum protein Electrophoresis:

NAME OF INVESTIGATIONNO. OF TESTS IN 2013
ELECTROPHORESIS36
IMMUNOFIXATION 04

C. Special clinical chemistry Lab, MAMC

Serum protein Electrophoresis:


NAME OF INVESTIGATIONNO. OF TESTS IN 2013
Test for Bence Jones proteins71 tests
Screening tests for porphyria10 tests
Stone Analysis51 tests

D. Electrochemiluminiscence lab, MAMC:

The following investigations are done on Monday and Thursday

NAME OF INVESTIGATIONNAME OF INVESTIGATION
TSHAFP
FT4ß HCG
FT3CEA
LHINSULIN
FSHPTH
PROLACTINDHEA
FERRITINE2
PSAAnti TPO
TESTOSTERONEFOLIC ACID
CORTISOLCA 125
VITAMIN D3PROGESTERONE
VITAMIN B12-----

No.of tests done in Electrochemiluminescence Lab in 2013:

MonthTotal no. of investigations
January---
February1,038
March1,221
April1,033
May938
June593
July838
August1,297
September1,964
October1,337
November1,213
December1,606
Total13,078